When applied topically to the skin, peptides act as messengers molecules, triggering skin cells to perform specific functions like building collagen, elastin and hyaluronic acid as well regulating the production of the pigment melanin which causes uneven skin tone. Young skin is active, low in pH (more acidic) than older skin and full of cellular activity which declines with age. The use of cosmetics and products (yes, moisturisers by themselves will reduce cell signalling! As well as UV exposure.
Peptides are a great asset to activate your skin when used in a sequential regime that increases cell turnover and stimulates the cell (Exfoliants & Retinoids). Mild to moderate acute inflammation (with retinoids and antioxidants) are often purposely induced in individuals with sensitive damage skin barriers (chronic inflammation).
Stimulate MP compromises of multiple peptides (regulating various cellular activities) at potent concentrations requiring application only in drops (two on the average!).
The base of the formulation contains hyaluronic acid as we expect this to combat dryness due to retinoids and exfoliants. As a standalone, it is an excellent eye serum.
- 05% Matrixyl Synthe’6
- 16% Matrixyl 3000
- 15% Syn-Coll
- 08% Argireline
- 08% Leuphasyl
- 05% Melanostatine-5
- 05% Aldenine
- 30% Peptamide-6
Aqua (Water), Glycerin, Hexapeptide-11, Butylene Glycol, Phenoxyethanol, (<1%) Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Pentapeptide-18, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Tripeptide-1, Nonapeptide-1, Palmitoyl Tripeptide-38, Hydrolyzed Soy Protein, Sodium Hyaluronate (L), Hydrolyzed Wheat Protein, Carbomer, Polysorbate 20, Ethylhexylglycerin, Hydroxypropyl Cyclodextrin, Caprylyl Glycol, Dextran, Xanthan Gum, Potassium Sorbate, O-cymen-5-OL
Tips & Suggestions
- As emphasised above, peptides are at the top of the clinical skincare pyramid. Ideally, the skin is already using:
- AHAs: Continuously exfoliated with glycolic and lactic acid as less dead skin increases penetration of active ingredients
- Antioxidants: A reservoir of l-ascorbic acid lowers oxidative stress/damaging free radical level) that impair cellular function and signalling.
- Retinoid: Repair cell nuclear function, decrease inflammatory mediators and repair DNA making the cell production facilities respond quickly to external messages by peptides.
Apply a max of 3-4 drops to clean face & lightly dab around the eye area morning & evening.
- For external use only
- Discontinue use if redness or irritation occurs
- Avoid contact with eyes
- Keep out of reach of children.
- Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature. Clin Cosmet Investig Dermatol. 2016; 9: 411–419.
- Cosmeceutical peptides. Dermatol Ther. Sep-Oct 2007;20(5):343-9. doi: 10.1111/j.1529-8019.2007.00148.x.
- Linder, J. The science behind peptides. Plast. Surg. Nurs. 2012, 32, 71–72. [CrossRef] [PubMed]
- Rull, M.; Davi, C.; Cañadas, E.; Almiñana, N.; Delgado, R. Peptide Approach to Enhance Anti-wrinkle Efficacy Between Injections.
- Farzam Gorouhi. Topical Peptides and Proteins for Aging Skin: Textbook of Aging Skin pp 1089-1117